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看不出什么问题。上例子看看

获取实际行数

Dim App As New MSExcel.Application

Dim Wb As MSExcel.WorkBook = App.WorkBooks.Open("F:\H\问题测试\abc.xls")

Dim Ws As MSExcel.WorkSheet = Wb.WorkSheets(1)

Dim r = App.ActiveSheet.Range("A65536").End(MsExcel.XlDirection.xlUp).Row

Output.Show(Ws.UsedRange.Rows.Count)

Output.Show(r)

Dim Rg As MSExcel.Range = Ws.Rows("1:" & r)

Output.Show(Rg.Rows.Count)

App.quit

具体问题上传文件测试

用法差不多

Dim App As New MSExcel.Application

Dim Wb As MSExcel.WorkBook = App.WorkBooks.Open("F:\H\问题测试\abc.xls")

Dim Ws As MSExcel.WorkSheet = Wb.WorkSheets(1)

Dim i = ws.Range("iv1").End(MsExcel.XlDirection.xlToLeft).Column

msgbox("第一行最后一个非空单元格列号为" & i)

App.quit

Dim App As New MSExcel.Application

Dim Wb As MSExcel.WorkBook = App.WorkBooks.Open(ProjectPath & "EXCEL测试文件\" & "1.xlsx")

Dim Ws As MSExcel.WorkSheet = Wb.WorkSheets(1)

Dim rowsmax As Integer = 0

Dim colsmax As Integer = 0

Dim rg = ws.usedRange

For i As Integer =1 To rg.Columns.count

Dim r = ws.cells(100000,i).End(MsExcel.XlDirection.xlUp).Row

If r > RowsMax Then

RowsMax = r

End If

For i As Integer = 1 To rowsMax

Dim r = ws.cells(i,200).End(MsExcel.XLDirection.xlToLeft).Column

If r > ColsMax Then

ColsMax = r

End If

App.quit

msgbox(RowsMax)

msgbox(colsmax)

设置成Execl可以支持的最大值不就行了，具体上网搜搜

Dim App As New MSExcel.Application

Dim Wb As MSExcel.WorkBook = App.WorkBooks.Open(ProjectPath & "EXCEL测试文件\" & "test20.xls")

Dim Ws As MSExcel.WorkSheet = Wb.WorkSheets(1)

Dim rowsmax As Integer = 0

Dim colmax As Integer = 0

Dim rg = Ws.UsedRange

'Dim FirstRow As Integer = Ws.Range("A1:d1").End(MSExcel.XlDirection.xlDown).Row

'msgbox(firstrow)

For i As Integer =1 To rg.Columns.count

Dim r = ws.cells(1000,i).End(MsExcel.XlDirection.xlUp).Row

If r > RowsMax Then

RowsMax = r

End If

For i As Integer = 1 To rowsMax

Dim r = ws.cells(i,200).End(MsExcel.XLDirection.xlToLeft).Column

If r > ColMax Then

ColMax = r

End If

rg = Ws.Range(Ws.Cells(1,1), Ws.Cells(RowsMax,ColMax ))

Dim ary = rg.value

'msgbox(rg.Rows.count)

'msgbox("读取列:" & rg.Columns.count & "," & "实际列:" & ColMax & "," & "实际行:" & RowsMax )

For i As Integer = 1 To rowsmax

For j As Integer = 1 To Colmax

If ary(i,j) <> Nothing Then

Dim dr As DataRow = DataTables("表A").AddNew

dr("第一列") = ary(i, j)

End If

App.quit

'msgbox(colsmax)

'msgbox(RowsMax)

设置实际的数据范围

如果第一列和第一行都为空Ws.UsedRange是不包含第一列和第一行的

主题：老师帮忙看看这个判断和循环是不是有问题？